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Soy Dietary Intervention in HIV+ ART-treated Individuals - Preliminary In-vitro HIV-Uninfected Conditions

Phimsouay, Sylvia
http://rave.ohiolink.edu/etdc/view?acc_num=osu1500350144066958

Abstract Details

2017, Master of Science, Ohio State University, Allied Medicine.
The production and dissemination of antiretroviral therapy (ART) has improved the longevity of the ART-treated HIV-infected individual via improved immune system function; it has also raised concerns regarding increased risk of cardiovascular disease (CVD) morbidity and mortality in this specific population. HIV-infection results in chronic immune activation and inflammation, which may play an important role in the increased risk of CVD. Drug intervention with statins has been shown to lower inflammatory markers, decrease carotid intima media thickness (cIMT) - which is significant in determining CVD progression - and improve the lipid profile in an HIV-infected population. A soy-based dietary intervention could serve as a potential non-drug therapy method for improving the morbidity and mortality of CVD in the HIV-infected population and has been shown to act as a natural modulator of lipid profiles and pro-inflammatory cytokines in men with hypercholesterolemia and prostate cancer. We hypothesize that soy treatment will reduce pro-inflammatory lipids, immune activation, and inflammation in HIV-infected ART-treated individuals, and as a correlate, potentially reduce their risk of morbidity due to CVD.
Nicholas Funderburg (Advisor)
41 p.
Health Sciences; Immunology
Soy Dietary Intervention; HIV ART treated Individuals

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Citations

  • Phimsouay, S. (2017). Soy Dietary Intervention in HIV+ ART-treated Individuals - Preliminary In-vitro HIV-Uninfected Conditions [Master's thesis, Ohio State University]. OhioLINK Electronic Theses and Dissertations Center. http://rave.ohiolink.edu/etdc/view?acc_num=osu1500350144066958

    APA Style (7th edition)

  • Phimsouay, Sylvia . Soy Dietary Intervention in HIV+ ART-treated Individuals - Preliminary In-vitro HIV-Uninfected Conditions. 2017. Ohio State University, Master's thesis. OhioLINK Electronic Theses and Dissertations Center, http://rave.ohiolink.edu/etdc/view?acc_num=osu1500350144066958.

    MLA Style (8th edition)

  • Phimsouay, Sylvia . "Soy Dietary Intervention in HIV+ ART-treated Individuals - Preliminary In-vitro HIV-Uninfected Conditions." Master's thesis, Ohio State University, 2017. http://rave.ohiolink.edu/etdc/view?acc_num=osu1500350144066958

    Chicago Manual of Style (17th edition)

osu1500350144066958
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© 2017, all rights reserved.
This open access ETD is published by The Ohio State University and OhioLINK.