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Thesis-Final.pdf (711.47 KB)
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Abstract Header
Association of Dietary Patterns, Inflammatory Biomarkers, and Physical Functioning among Older Female Cancer Survivors
Author Info
Schmalenberger, Megan Ann
Permalink:
http://rave.ohiolink.edu/etdc/view?acc_num=osu1586963179194652
Abstract Details
Year and Degree
2020, Master of Science, Ohio State University, Health and Rehabilitation Sciences.
Abstract
Background: Nutritional status in cancer survivors is complex and often influenced by age, cancer type and stage, comorbidities, and physical function. Systemic inflammation often occurs in conjunction of carcinogenesis and this can increase risk for malnutrition. Objective: To assess the diet quality of older cancer survivors, and its association of inflammatory biomarkers and physical functioning. Methods: Participants completed study surveys via mail or phone to assess physical health (RAND-36), diet quality (DHQ-II, HEI-2015), and BMI. Participant diagnosis, comorbidities, inflammation (CRP, albumin) were obtained via the electronic medical record. Analyses: Descriptive statistics and Pearson’s correlations were used to analyze data. Results: The average age of participants (n=168) was 73.6+8.4 years. Mean physical functioning score was 59.6+24.1 out of a possible 100. Moderate negative correlation between physical functioning and self-rated health was observed (r= -.57, p<0.01). Moderate positive correlation was observed among physical functioning and albumin (r=.42, p<0.01). Mean HEI score was 66.39+10.0. A weak positive correlation was observed between total HEI score and physical functioning (r=.34, p<0.01). Moderate negative correlation between total HEI score and CRP was observed (r= -.42, p<0.05). Strong negative correlation was observed between CRP and albumin (r= -.74, p<0.01), and a moderate negative correlation between CRP and physical functioning (r= -.52, p<0.01). Conclusions: Identifying dietary patterns and inflammatory markers is pertinent to improve the survival and long-term health of cancer survivors. Future larger cohort studies of cancer survivors with multiple measurements are needed to confirm findings.
Committee
Jessica Krok-Schoen, Dr. (Advisor)
Colleen Spees, Dr. (Committee Member)
Anna Maria Bittoni (Committee Member)
Pages
70 p.
Subject Headings
Nutrition
;
Oncology
Keywords
Cancer Survivors, Dietary Patterns
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Citations
Schmalenberger, M. A. (2020).
Association of Dietary Patterns, Inflammatory Biomarkers, and Physical Functioning among Older Female Cancer Survivors
[Master's thesis, Ohio State University]. OhioLINK Electronic Theses and Dissertations Center. http://rave.ohiolink.edu/etdc/view?acc_num=osu1586963179194652
APA Style (7th edition)
Schmalenberger, Megan .
Association of Dietary Patterns, Inflammatory Biomarkers, and Physical Functioning among Older Female Cancer Survivors.
2020. Ohio State University, Master's thesis.
OhioLINK Electronic Theses and Dissertations Center
, http://rave.ohiolink.edu/etdc/view?acc_num=osu1586963179194652.
MLA Style (8th edition)
Schmalenberger, Megan . "Association of Dietary Patterns, Inflammatory Biomarkers, and Physical Functioning among Older Female Cancer Survivors." Master's thesis, Ohio State University, 2020. http://rave.ohiolink.edu/etdc/view?acc_num=osu1586963179194652
Chicago Manual of Style (17th edition)
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Document number:
osu1586963179194652
Download Count:
70
Copyright Info
© 2020, some rights reserved.
Association of Dietary Patterns, Inflammatory Biomarkers, and Physical Functioning among Older Female Cancer Survivors by Megan Ann Schmalenberger is licensed under a Creative Commons Attribution-NonCommercial-NoDerivs 3.0 Unported License. Based on a work at etd.ohiolink.edu.
This open access ETD is published by The Ohio State University and OhioLINK.