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DEVELOPMENT OF THE PRIMARY AUDITORY CORTEX IN THE FERRET

ADLER, BETHANY ALYCE
http://rave.ohiolink.edu/etdc/view?acc_num=ucin1060893159

Abstract Details

2003, MA, University of Cincinnati, Allied Health Sciences : Communication Sciences and Disorders.
The purpose of this study was to examine the development of the primary auditory cortex (AI) in the ferret. This study was conducted using five sable ferrets (Mustela putorius furo) of the following ages: (1) postnatal age 11 (2) postnatal age 18 (3) postnatal age 25 (4) postnatal age 32 and (5) postnatal age 63. Each subject was perfused transcardially with physiological saline, followed by tissue fixation using 4% paraformaldehyde in 0.1 M sodium phosphate buffer (pH 7.4). Each ferret was then decapitated, and the skull was dissected to allow removal of the brain, which was stored in the same fixative. The auditory cortex of each ferret was dissected from the whole brain and subsequently embedded in a gelatin and egg yolk solution. The embedded tissue blocks were then immersed in 4% paraformaldehyde for 72 hours and then sectioned using a vibrotome. Sections cut in 70 µm increments were stained using cresyl violet, and qualitatively analyzed using a light microscope. The results of this study supported previous findings, indicating that the laminar structure of the primary auditory cortex is in place by postnatal day 18 in the ferret. Additional studies investigating the laminar structure in younger ferrets and utilizing cell counts is recommended.
Dr. Susan Stanton (Advisor)
44 p.
auditory cortex; development; primary auditory cortex; ferret; neocortex

Recommended Citations

Citations

  • ADLER, B. A. (2003). DEVELOPMENT OF THE PRIMARY AUDITORY CORTEX IN THE FERRET [Master's thesis, University of Cincinnati]. OhioLINK Electronic Theses and Dissertations Center. http://rave.ohiolink.edu/etdc/view?acc_num=ucin1060893159

    APA Style (7th edition)

  • ADLER, BETHANY. DEVELOPMENT OF THE PRIMARY AUDITORY CORTEX IN THE FERRET. 2003. University of Cincinnati, Master's thesis. OhioLINK Electronic Theses and Dissertations Center, http://rave.ohiolink.edu/etdc/view?acc_num=ucin1060893159.

    MLA Style (8th edition)

  • ADLER, BETHANY. "DEVELOPMENT OF THE PRIMARY AUDITORY CORTEX IN THE FERRET." Master's thesis, University of Cincinnati, 2003. http://rave.ohiolink.edu/etdc/view?acc_num=ucin1060893159

    Chicago Manual of Style (17th edition)

ucin1060893159
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© 2003, all rights reserved.
This open access ETD is published by University of Cincinnati and OhioLINK.