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Maternal adiposity and plasma concentrations of leptin and adiponectin

Ahire, Shwetal
http://rave.ohiolink.edu/etdc/view?acc_num=ucin1250701408

Abstract Details

2009, MS, University of Cincinnati, Allied Health Sciences : Nutrition.
Objective: The purpose of this project was to determine the relationship of maternal adiposity to the adipokines, adiponectin and leptin.Design: Prospective cohort study. Subjects: Healthy, non-smoking pregnant women were recruited from the University Hospital's Obstetric Clinics (Cincinnati, Ohio) when they presented for their first prenatal visit in gestational week 8-16. Main Outcome measure:Anthropometric parameters, plasma leptin and adiponectin Methods: Healthy non-smoking pregnant women enrolled. Anthropometric parameters such as height, weight, mid-arm circumference, wrist circumference, skinfold thickness (biceps and thigh) were measured during early prenatal visit (8 to 16 weeks of gestation). Pre-pregnancy BMI (Body Mass Index) was obtained by self report. From the venous blood draw plasma leptin and adiponectin levels were analyzed (ELISA method). Bivariate correlation analysis was performed by using SPSS (Vs 14.0, Chicago, IL). Results: A strong positive association between pre pregnancy BMI and plasma leptin levels and a strong negative association between pre-pregnancy BMI and plasma adiponectin levels were found. Mid-arm circumference had a positive association with plasma leptin and a negative association with plasma adiponectin. Wrist circumference, biceps skinfold and thigh skinfold had a negative association with plasma adiponectin concentrations. Pre pregnancy BMI was significantly related to the anthropometric parameters measured in early pregnancy. Conclusion: Adiposity prior to pregnancy and during early pregnancy period was associated with higher levels of leptin and lower levels of adiponectin in early to mid pregnancy.
Debra Krummel, PhD RD (Committee Chair)
Seung-Yeon Lee, PhD (Committee Member)
54 p.
Nutrition
pregnancy; skinfold; leptin; adiponectin; obesity

Recommended Citations

Citations

  • Ahire, S. (2009). Maternal adiposity and plasma concentrations of leptin and adiponectin [Master's thesis, University of Cincinnati]. OhioLINK Electronic Theses and Dissertations Center. http://rave.ohiolink.edu/etdc/view?acc_num=ucin1250701408

    APA Style (7th edition)

  • Ahire, Shwetal. Maternal adiposity and plasma concentrations of leptin and adiponectin. 2009. University of Cincinnati, Master's thesis. OhioLINK Electronic Theses and Dissertations Center, http://rave.ohiolink.edu/etdc/view?acc_num=ucin1250701408.

    MLA Style (8th edition)

  • Ahire, Shwetal. "Maternal adiposity and plasma concentrations of leptin and adiponectin." Master's thesis, University of Cincinnati, 2009. http://rave.ohiolink.edu/etdc/view?acc_num=ucin1250701408

    Chicago Manual of Style (17th edition)

ucin1250701408
779
© 2009, all rights reserved.
This open access ETD is published by University of Cincinnati and OhioLINK.