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Discovery of overlapping 1-closed biclusters

Banerjee, Abhik
http://rave.ohiolink.edu/etdc/view?acc_num=ucin1352396960

Abstract Details

2012, MS, University of Cincinnati, Engineering and Applied Science: Computer Science.
The aim of this thesis is to find overlapping pairs of 1-closed biclusters from two different but related heterogeneous relations. Our algorithm generates 1-closed biclusters by expanding closed biclusters. In the process of generating 1-closed bicluster we allow to add limited “0”s to the closed bicluster. A bicluster with a limited number of such “0”s still captures the close link among the two sets and additionally, help predict the edges that may be missing in the original dataset. We have designed a novel algorithm, and tested it using a synthetic and two biomedical datasets from the field of genomics. We predict target disease – gene relationships which are relatively weakly linked as compared to a closed bicluster in the biomedical datasets. With the help of the synthetic dataset we also show that our algorithm is generic and can be applied to various fields including social networking and bioinformatics.
Raj Bhatnagar, PhD (Committee Chair)
Anil Jegga, DVM MRes (Committee Member)
Yizong Cheng, PhD (Committee Member)
79 p.
Computer Science
PubMed Ids; 1-closed biclusters; closed biclusters; Orphan Disease;

Recommended Citations

Citations

  • Banerjee, A. (2012). Discovery of overlapping 1-closed biclusters [Master's thesis, University of Cincinnati]. OhioLINK Electronic Theses and Dissertations Center. http://rave.ohiolink.edu/etdc/view?acc_num=ucin1352396960

    APA Style (7th edition)

  • Banerjee, Abhik. Discovery of overlapping 1-closed biclusters. 2012. University of Cincinnati, Master's thesis. OhioLINK Electronic Theses and Dissertations Center, http://rave.ohiolink.edu/etdc/view?acc_num=ucin1352396960.

    MLA Style (8th edition)

  • Banerjee, Abhik. "Discovery of overlapping 1-closed biclusters." Master's thesis, University of Cincinnati, 2012. http://rave.ohiolink.edu/etdc/view?acc_num=ucin1352396960

    Chicago Manual of Style (17th edition)

ucin1352396960
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© 2012, all rights reserved.
This open access ETD is published by University of Cincinnati and OhioLINK.