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Better diagnosis of coronary artery disease using combined trans-lesional hemodynamics and anatomical information

Peelukhana, Srikara Vishwanath
http://rave.ohiolink.edu/etdc/view?acc_num=ucin1407406861

Abstract Details

2014, PhD, University of Cincinnati, Engineering and Applied Science: Mechanical Engineering.
Invasive diagnosis of coronary artery disease utilizes either anatomical or functional measurements. The objective of this dissertation is to improve the diagnosis of coronary artery disease such as epicardial stenosis and microvascular disease using combined anatomical (%area stenosis: %AS) and functional (pressure and flow) parameter, lesion flow coefficient (LFC). The LFC is defined as the ratio of %AS to the square root of the ratio of the pressure drop across the stenosis to the dynamic pressure in the throat region). The hypothesis is that the LFC can better delineate the contributions of epicardial stenosis and microvascular disease, under clinical scenario. To test the hypothesis, three Specific Aims are formulated: 1.
Rupak Banerjee, Ph.D P.E. (Committee Chair)
Imran Arif, MD (Committee Member)
Hanan Kerr, M.D. F.A.C.C. (Committee Member)
Mohamed Effat, Ph.D. (Committee Member)
Ronald Huston, Ph.D. (Committee Member)
Teik Lim, Ph.D. (Committee Member)
Bingjing Su, Ph.D. (Committee Member)
181 p.
Individual and Family Studies; Mechanical Engineering
stenosis; mechanical engineering

Recommended Citations

Citations

  • Peelukhana, S. V. (2014). Better diagnosis of coronary artery disease using combined trans-lesional hemodynamics and anatomical information [Doctoral dissertation, University of Cincinnati]. OhioLINK Electronic Theses and Dissertations Center. http://rave.ohiolink.edu/etdc/view?acc_num=ucin1407406861

    APA Style (7th edition)

  • Peelukhana, Srikara Vishwanath. Better diagnosis of coronary artery disease using combined trans-lesional hemodynamics and anatomical information. 2014. University of Cincinnati, Doctoral dissertation. OhioLINK Electronic Theses and Dissertations Center, http://rave.ohiolink.edu/etdc/view?acc_num=ucin1407406861.

    MLA Style (8th edition)

  • Peelukhana, Srikara Vishwanath. "Better diagnosis of coronary artery disease using combined trans-lesional hemodynamics and anatomical information." Doctoral dissertation, University of Cincinnati, 2014. http://rave.ohiolink.edu/etdc/view?acc_num=ucin1407406861

    Chicago Manual of Style (17th edition)

ucin1407406861
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© 2014, all rights reserved.
This open access ETD is published by University of Cincinnati and OhioLINK.
Release 3.2.12