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Availability of Fermentable Nutrients Affect Gut Microbiota Composition

Mehta, Trupthi
http://rave.ohiolink.edu/etdc/view?acc_num=wright1535384558865901

Abstract Details

2018, Master of Science (MS), Wright State University, Biochemistry and Molecular Biology.
Recent studies have increasingly established the role of gut microbiota in human health and disease. Diseases such as inflammatory bowel disease, colon cancer, cardiovascular disease and many neurological disorders have been linked to specific gut microbiota composition and disturbances. There have also been attempts in recent years to modulate gut microbial composition with the use of prebiotics and probiotics to promote healthy gut and prevent diseases. This thesis investigates whether the availability of fermentable nutrients high in fiber and antioxidants such as found in green coffee, roasted coffee, and salami infused with various prebiotics altered the composition and abundance of gut microbiota. A significant difference in the composition of microbial genera was found among samples containing fermentable nutrients compared to control. Our study also showed there is a difference in abundance of Bifidobacterium, Bacteroides and Dorea, which were the top 3 most abundant genera among salami samples. Also, there was a difference in abundance of Escherichia/Shigella, Bacteroides and Bifidobacterium, which were the top 3 abundant genera among the coffee samples.
Oleg Paliy, Ph.D. (Advisor)
John Paietta, Ph.D. (Committee Member)
Kwang-Jin Cho, Ph.D. (Committee Member)
43 p.
Biochemistry; Bioinformatics; Microbiology
gut microbiota; fermentable nutrients

Recommended Citations

Citations

  • Mehta, T. (2018). Availability of Fermentable Nutrients Affect Gut Microbiota Composition [Master's thesis, Wright State University]. OhioLINK Electronic Theses and Dissertations Center. http://rave.ohiolink.edu/etdc/view?acc_num=wright1535384558865901

    APA Style (7th edition)

  • Mehta, Trupthi. Availability of Fermentable Nutrients Affect Gut Microbiota Composition . 2018. Wright State University, Master's thesis. OhioLINK Electronic Theses and Dissertations Center, http://rave.ohiolink.edu/etdc/view?acc_num=wright1535384558865901.

    MLA Style (8th edition)

  • Mehta, Trupthi. "Availability of Fermentable Nutrients Affect Gut Microbiota Composition ." Master's thesis, Wright State University, 2018. http://rave.ohiolink.edu/etdc/view?acc_num=wright1535384558865901

    Chicago Manual of Style (17th edition)

wright1535384558865901
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This open access ETD is published by Wright State University and OhioLINK.