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Quantitated Effects of Nutritional Supplementation on Exercise Induced Sweat

Browder, Andrew Blake Austin
http://orcid.org/0000-0002-4710-7353
http://rave.ohiolink.edu/etdc/view?acc_num=wright1616769068342984

Abstract Details

2021, Master of Science (MS), Wright State University, Biochemistry and Molecular Biology.
Discovery studies have identified many metabolites contained in human sweat. However, quantitative analysis of the sweat metabolome content remains mostly unknown. Furthermore several attributes, including rate, have been defined to affect sweat metabolite content, while other effectors, like diet, remain unknown. This study works to quantitatively define the metabolite impact caused by nutritional supplementation. To better understand the effect diet plays, a LC-MS method was developed focusing on improving resolution and peak width. While the literature provided examples of how diet affected sweat metabolite concentrations, the long-term effects of diet have not been explored. The experiment described here attempts to fill that gap. Partial data separation was found among groups ingesting high and low nutritional supplementation. Several subjects given the high nutritional supplementation had decreased sweat metabolite concentrations after twelve weeks. These results suggest nutritional supplementation can impact the sweat metabolome, and diet should be considered in biomarker discovery experimentation.
Sean Harshman, Ph.D. (Committee Co-Chair)
Nicholas V. Reo, Ph.D. (Committee Co-Chair)
Michael P. Markey, Ph.D. (Committee Member)
111 p.
Analytical Chemistry; Biochemistry; Molecular Biology; Molecular Chemistry
Sweat; Metabolomics; LC-MS

Recommended Citations

Citations

  • Browder, A. B. A. (2021). Quantitated Effects of Nutritional Supplementation on Exercise Induced Sweat [Master's thesis, Wright State University]. OhioLINK Electronic Theses and Dissertations Center. http://rave.ohiolink.edu/etdc/view?acc_num=wright1616769068342984

    APA Style (7th edition)

  • Browder, Andrew. Quantitated Effects of Nutritional Supplementation on Exercise Induced Sweat. 2021. Wright State University, Master's thesis. OhioLINK Electronic Theses and Dissertations Center, http://rave.ohiolink.edu/etdc/view?acc_num=wright1616769068342984.

    MLA Style (8th edition)

  • Browder, Andrew. "Quantitated Effects of Nutritional Supplementation on Exercise Induced Sweat." Master's thesis, Wright State University, 2021. http://rave.ohiolink.edu/etdc/view?acc_num=wright1616769068342984

    Chicago Manual of Style (17th edition)

wright1616769068342984
834
© 2021, some rights reserved.Creative Commons License Quantitated Effects of Nutritional Supplementation on Exercise Induced Sweat by Andrew Blake Austin Browder is licensed under a Creative Commons Attribution-NonCommercial-NoDerivs 3.0 Unported License. Based on a work at etd.ohiolink.edu.
This open access ETD is published by Wright State University and OhioLINK.