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Profiling of the Talaromyces (Penicillium) marneffei Secretome

Abstract Details

2020, Master of Science in Biological Sciences, Youngstown State University, Department of Biological Sciences and Chemistry.
This study was focused on profiling the secretome of the thermally dimorphic fungus Talaromyces marneffei via SDS-PAGE with the intent to identify proteins which are differentially and/or preferentially expressed in either growth phase. SDS-PAGE analysis revealed several protein bands which showed differential expression between growth phases. Were the Coronavirus pandemic to not have impacted laboratory work, this study would be continued by sequencing the identified protein bands via tandem MS. Additionally these amino acid sequences would be used to create primers for qRT-PCR analysis to quantify the levels of expression differences between growth phases.
Chester Cooper, Jr./PhD (Advisor)
David Asch, PhD (Committee Member)
John Caguiat, PhD (Committee Member)
Xiang Jia Min, PhD (Committee Member)
Gary Walker, PhD (Committee Member)
48 p.

Recommended Citations

Citations

  • Lomman, B. C. (2020). Profiling of the Talaromyces (Penicillium) marneffei Secretome [Master's thesis, Youngstown State University]. OhioLINK Electronic Theses and Dissertations Center. http://rave.ohiolink.edu/etdc/view?acc_num=ysu1596125178422383

    APA Style (7th edition)

  • Lomman, Brett. Profiling of the Talaromyces (Penicillium) marneffei Secretome. 2020. Youngstown State University, Master's thesis. OhioLINK Electronic Theses and Dissertations Center, http://rave.ohiolink.edu/etdc/view?acc_num=ysu1596125178422383.

    MLA Style (8th edition)

  • Lomman, Brett. "Profiling of the Talaromyces (Penicillium) marneffei Secretome." Master's thesis, Youngstown State University, 2020. http://rave.ohiolink.edu/etdc/view?acc_num=ysu1596125178422383

    Chicago Manual of Style (17th edition)